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Evidence and Publications

Our investigational therapies are backed by world-class evidence

Nature Medicine

Non-invasive spinal cord electrical stimulation for arm and hand function in chronic tetraplegia: a safety and efficacy trial

Up-LIFT Pivotal Study

Positive topline results reported from 65 participant clinical trial in Europe and North America that evaluated the safety and effectiveness of non-invasive ARCEX Therapy to improve upper extremity strength and function in people with SCI

Nature Medicine

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson’s disease

Nature

Walking naturally after spinal cord injury using a brain–spine interface

Nature

The neurons that restore walking after paralysis

Nature Medicine

Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

Nature

Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury

Nature Medicine

Spinal cord repair: advances in biology and technology

Science Translational Medicine

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

Nature

Targeted neurotechnology restores walking in humans with spinal cord injury

Nature Neuroscience

Electrical spinal cord stimulation must preserve proprioception to enable locomotion in humans with spinal cord injury

Nature

Required growth facilitators propel axon regeneration across complete spinal cord injury

Nature Neuroscience

Cortico–reticulo–spinal circuit reorganization enables functional recovery after severe spinal cord contusion

Science Translational Medicine

A multidirectional gravity-assist algorithm that enhances locomotor control in patients with stroke or spinal cord injury

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